Abstract
This issue of the American Journal of Bioethics features an article on the importance of building trusting relationships for the successful creation of research repositories that include biospecimens and data records from under-represented ethnic and racial groups in the U.S. Other researchers have made note of this challenge (including most of this research group in relation to learning health system research). This editorial will focus on two important points raised by Kraft et al. and discussed in the outstanding set of commentaries.